Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.60 |
| ▸ | HTR7 | P34969 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647687 | 0.91 | HTR1A (0.65) | HTR1AHTR7DRD2HTR2A | |
| SCHEMBL9647603 | 0.86 | ALDH1A1 (0.50) | HTR1AHTR7ALDH1A1LMNAMAPT | |
| SCHEMBL9647522 | 0.85 | TSHR (0.49) | HTR1AHTR7ALDH1A1RAB9AKDM4E | |
| SCHEMBL9647579 | 0.82 | KDM4E (0.46) | HTR1AALDH1A1KDM4EDRD2HTR2A | |
| SCHEMBL9645860 | 0.81 | HTR1A (0.55) | HTR1AHTR7ALDH1A1LMNAMAPT | |
| SCHEMBL9646321 | 0.81 | KDM4E (0.50) | HTR1AALDH1A1RAB9AKDM4EKMT2A | |
| SCHEMBL9646680 | 0.80 | NPC1 (0.52) | HTR1AALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL9646799 | 0.78 | KDM4E (0.54) | HTR1AHTR7ALDH1A1LMNAMAPT | |
| SCHEMBL9589114 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL9588921 | 0.77 | KDM4E (0.53) | ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |