Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646389 | 0.85 | ALOX5 (0.70) | ALOX5PKMKMT2AOPRM1OPRD1 | |
| SCHEMBL9596545 | 0.83 | ALOX5 (1.00) | ALOX5PKMMAPK10KDM4EL3MBTL1 | |
| SCHEMBL9646981 | 0.82 | ALOX5 (0.66) | ALOX5PKMKMT2AOPRM1OPRD1 | |
| SCHEMBL9645173 | 0.74 | ALOX5 (0.54) | ALOX5PKMKMT2AOPRM1OPRD1 | |
| SCHEMBL9647127 | 0.73 | ALOX5 (0.53) | ALOX5CYP2C9CYP2C19KDM4E | |
| SCHEMBL9646928 | 0.72 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL5864063 | 0.71 | ALDH1A1 (0.51) | ALOX5PKMMAPK10KDM4E | |
| Hydrochloric Acid SCHEMBL19896459 | 0.70 | SRC (0.61) | PKMKMT2AOPRM1OPRD1MAPK10 | |
| SCHEMBL18149885 | 0.69 | NPSR1 (0.49) | ALOX5L3MBTL1 | |
| SCHEMBL9646339 | 0.69 | ALOX5 (0.51) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |