Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.59 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581905 | 0.90 | NPSR1 (0.55) | PDK1PDK2PDK3PDK4NPSR1 | |
| SCHEMBL29435026 | 0.88 | HDAC3 (0.58) | NPSR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL222876 | 0.88 | HDAC3 (0.58) | NPSR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31396764 | 0.87 | KMT2A (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7439456 | 0.87 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29867230 | 0.86 | CYP1A2 (0.61) | NPSR1L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL11947174 | 0.86 | ALDH1A1 (0.60) | PDK1PDK2PDK3PDK4NPSR1 | |
| SCHEMBL5337975 | 0.86 | CYP1A2 (0.61) | NPSR1L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL11080324 | 0.85 | HDAC3 (0.56) | NPSR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29029431 | 0.84 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017476-A1 | BENZOYLPHENYL PYRIDINYLTHIAZOLIDINE COMPOUNDS AS PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5120751-A | Platelet activating factor antagonist | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |