Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435026 | 1.00 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7439456 | 0.98 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5337975 | 0.89 | CYP1A2 (0.61) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29867230 | 0.89 | CYP1A2 (0.61) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11080324 | 0.88 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9646358 | 0.88 | PDK1 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL28424639 | 0.88 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL28424642 | 0.88 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29029431 | 0.87 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL31396764 | 0.87 | KMT2A (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611814-B | Compound containing 2-amino imidazole ring, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2024-11-19 | — | — | CN | claimed |
| CN-115611814-A | Compound containing 2-aminoimidazole ring and preparation method and application thereof | 烟台新药创制山东省实验室 | 2023-01-17 | — | — | CN | claimed |
| CN-109503510-B | Antibacterial thiazole compound for preventing caries and preparation method thereof | 山东大学 | 2020-07-03 | — | — | CN | claimed |
| CN-109503510-A | A kind of thiazole compound and preparation method thereof of preventing decayed tooth antibacterial | 山东大学 | 2019-03-22 | — | — | CN | claimed |
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| US-20260144743-A1 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-05-28 | — | — | US | disclosed |
| EP-4746966-A1 | 4-AMINO-2,6-BIS(PHENYLMETHYLENE)CYCLOHEXANONES AND THEIR USE | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2026-05-27 | — | — | EP | disclosed |
| US-12570655-B2 | Cysteine covalent modifiers of AKT1 and uses thereof | TERREMOTO BIOSCIENCES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4699655-A2 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-02-25 | — | — | EP | disclosed |
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2026-01-29 | — | — | US | disclosed |
| US-12528785-B2 | MDM2 degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| WO-2025264818-A1 | STAT6 MODULATORS AND METHODS OF USES THEREOF | RAYTHERA, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0364767-A1 | Mercapto-acylamino acids useful in the treatment of cardiovascular disorders and as analgesics | SCHERING CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003364-A1 | MERCAPTO-ACYLAMINO ACIDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISORDERS AND AS ANALGESICS | SCHERING CORPORATION (US) | 1990-04-05 | — | — | WO | disclosed |
| US-4879309-A | ENKEPHALINASE INHIBITORS | SCHERING CORPORATION (US) | 1989-11-07 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4758552-A | Gonadoliberin derivatives containing an aromatic aminocarboxylic acid in the 6-position, pharmaceutical and veterinary compositions containing them and process for preparing same | INNOFINANCE ALTALANOS INNOVACIOS PENZINTEZET (HU) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT3 | HDAC3 29/4885HDAC1 45/4885HDAC2 56/4885 |
| US-20260144743-A1 | COMPOUNDS | CACNA1E, TMEM109, CACNA1C | HDAC3 878/4885HDAC1 1893/4885HDAC2 2429/4885 |
| US-12528785-B2 | MDM2 degraders and uses thereof | MDM2, ADRM1, RBX1 | HDAC3 723/4885HDAC1 562/4885HDAC2 1268/4885 |
| US-12570655-B2 | Cysteine covalent modifiers of AKT1 and uses thereof | AKT1, AKT2, AKT3 | HDAC3 187/4885HDAC1 223/4885HDAC2 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.