Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 3/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10402146 | 0.99 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10SLC37A4 | |
| SCHEMBL9648193 | 0.91 | RPS6KB1 (0.40) | KDM4EALDH1A1HPGDHSD17B10SLC37A4 | |
| Hydrochloric Acid SCHEMBL10402111 | 0.90 | RPS6KB1 (0.39) | KDM4EALDH1A1HPGDHSD17B10SLC37A4 | |
| SCHEMBL10402138 | 0.88 | TSHR (0.42) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9518223 | 0.82 | IAPP (0.31) | — | |
| SCHEMBL9647534 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2100736 | 0.78 | ADRA2A (0.36) | TSHR | |
| SCHEMBL10547608 | 0.77 | CYP19A1 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL9766367 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10SLC37A4 | |
| SCHEMBL28349037 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10SLC37A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |