SCHEMBL9766367

SCHEMBL9766367

CCCCC(CCCC)c1cccc(C(=O)O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CYSLTR2 Q9NS75 1/20 0.45
CYSLTR1 Q9Y271 1/20 0.45
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
SLC37A4 O43826 1/20 0.43
ALB P02768 1/20 0.42
MMP2 P08253 1/20 0.42
TSHR P16473 1/20 0.41
HMGB1 P09429 1/20 0.41
HNF4A P41235 1/20 0.40
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
LMNA P02545 1/20 0.39
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28349037 0.97 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL368880 0.96 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL5453793 0.94 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL342806 0.90 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL7795743 0.88 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL7792309 0.88 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDHSD17B10CYSLTR2
SCHEMBL9580940 0.84 SLC37A4 (0.51) ALDH1A1KDM4ECYSLTR2CYSLTR1KMT2A
SCHEMBL30768206 0.83 CYSLTR2 (0.49) ALDH1A1KDM4EHPGDCYSLTR2CYSLTR1
SCHEMBL7608942 0.83 CYSLTR2 (0.49) ALDH1A1KDM4EHPGDCYSLTR2CYSLTR1
SCHEMBL906284 0.81 ALDH1A1 (0.56) ALDH1A1KDM4ECYSLTR2CYSLTR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075416-A Suspending methanesulfonic acid and aromatic acid in aliphatic solvent, slowly adding unsaturated aromatic hydrocarbon RUTGERSWERKE AG (DE) 1991-12-24 US disclosed