Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399877 | 0.85 | PIM1 (0.49) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL7407417 | 0.81 | CLK4 (0.50) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL9650393 | 0.75 | GABRP (0.47) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL9256388 | 0.73 | ADORA3 (0.55) | PIM1RPS6KB1CSNK1DCLK2STK3 | |
| SCHEMBL21063203 | 0.72 | MAPT (0.50) | KDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL8094714 | 0.72 | GABRA2 (0.64) | GABRA1GABRA2GABRA5GABRA3PIM1 | |
| SCHEMBL7406885 | 0.72 | MAPK14 (0.45) | GABRA1GABRA2PIM1RPS6KB1CSNK1D | |
| SCHEMBL7403563 | 0.72 | FEN1 (0.43) | PIM1RPS6KB1CSNK1DCLK2STK3 | |
| SCHEMBL7402945 | 0.72 | SMN1; SMN2 (0.44) | GABRA1GABRA2GABRA5GABRA3PIM1 | |
| SCHEMBL10927900 | 0.72 | POLB (0.54) | GABRA1GABRA2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128338-A | Cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1992-07-07 | — | — | US | disclosed |