Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484229 | 0.89 | ADORA1 (0.43) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5474017 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL966489 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL921576 | 0.82 | L3MBTL1 (0.54) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL968790 | 0.78 | GRM5 (0.51) | ADORA1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29581363 | 0.78 | GRM5 (0.51) | ADORA1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25676388 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2XIAPBIRC2RAB9AKDM4E | |
| SCHEMBL10691212 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10691207 | 0.76 | ADORA1 (0.46) | SMN1; SMN2ADORA1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL126159 | 0.76 | RAB9A (0.68) | SMN1; SMN2RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557849-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2013-10-15 | — | — | US | disclosed |
| EP-2257168-B1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20110015236-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-20 | — | — | US | disclosed |
| EP-2257168-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer CropScience AG (DE) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009115556-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015236-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | CYP51A1, HAAO, HPD | SMN1; SMN2 4458/4885ADORA1 4680/4885CYP1A2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.