Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 3/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028353 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL31639294 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL9648801 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1159033 | 0.76 | BLM (0.48) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL11947918 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL568664 | 0.75 | LMNA (0.44) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL31032208 | 0.75 | LMNA (0.44) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL24012849 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL28055460 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL2461328 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |