Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649859 | 0.81 | TSPO (0.55) | ADORA3ADORA2AADORA1TP53 | |
| SCHEMBL4648097 | 0.73 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL4013052 | 0.71 | MAP3K11 (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9213247 | 0.70 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPT | |
| SCHEMBL11576284 | 0.70 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL28127173 | 0.69 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| Hydrochloric Acid SCHEMBL11578577 | 0.69 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL28127167 | 0.69 | MCL1 (0.58) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9649918 | 0.68 | CYP1A2 (0.56) | KMT2AALDH1A1 | |
| SCHEMBL9217903 | 0.68 | TSPO (0.59) | ALDH1A1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128338-A | Cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1992-07-07 | — | — | US | disclosed |