Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.56 |
| ▸ | ACACB | O00763 | 12/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764483 | 0.90 | ACACB (0.62) | ITGB3ITGA2BACACB | |
| SCHEMBL9650533 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BACACBCA12CA1 | |
| SCHEMBL9650513 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BACACBCA12CA1 | |
| SCHEMBL7300335 | 0.86 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL8732422 | 0.82 | HDAC8 (0.53) | ITGB3ITGA2BACACB | |
| SCHEMBL8732428 | 0.82 | HDAC8 (0.53) | ITGB3ITGA2BACACB | |
| SCHEMBL12203612 | 0.82 | ACACB (0.58) | ITGB3ITGA2BACACB | |
| SCHEMBL8732751 | 0.82 | ACACB (0.58) | ITGB3ITGA2BACACB | |
| SCHEMBL256796 | 0.81 | ACACB (0.62) | ACACB | |
| SCHEMBL8732743 | 0.81 | ACACB (0.50) | ITGB3ITGA2BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279213-B1 | FLUORESCENCE POLARIZATION IMMUNOASSAY FOR AMPHETAMINE/METHAMPHETAMINE | ABBOTT LABORATORIES (US) | 1992-10-21 | — | — | EP | disclosed |
| US-4952336-A | USING TWO FLUORESCEIN TRACER DERIVATIVES | ABBOTT LABORATORIES (US) | 1990-08-28 | — | — | US | disclosed |
| US-4868132-A | BINDING TO A FLUORESCEIN TYPE TRACER, PRETREATMENT WITH PERIODATE | ABBOTT LABORATORIES (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0279213-A1 | Fluorescence polarization immunoassay for amphetamine/methamphetamine | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |