Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136534 | 0.87 | HTT (0.35) | KMT2AHTTMEN1 | |
| SCHEMBL27342409 | 0.87 | — | — | |
| SCHEMBL13332956 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| SCHEMBL383436 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| SCHEMBL28418543 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| SCHEMBL9797557 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL5661 | 0.79 | — | — | |
| SCHEMBL10896455 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EMAPTKMT2AATM | |
| SCHEMBL3346344 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMAPTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162575-A | Reacting organic base with halogenated amide in solvent | OLIN CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |