Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | CYBB | P04839 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenothiazine SCHEMBL9715033 | 0.79 | NOX1 (0.64) | NOX1MAPTGAAALOX15MEN1 | |
| Phenothiazine SCHEMBL9727549 | 0.76 | NOX1 (0.57) | NOX1MAPTGAAALOX15MEN1 | |
| SCHEMBL4079174 | 0.73 | NOX1 (0.51) | NOX1MAPTGAAALOX15MEN1 | |
| SCHEMBL17284846 | 0.73 | NOX1 (0.57) | NOX1MAPTGAAALOX15MEN1 | |
| SCHEMBL240209 | 0.72 | NOX1 (0.59) | NOX1MAPTGAAALOX15MEN1 | |
| SCHEMBL8147738 | 0.71 | NOX1 (0.53) | NOX1MAPTGAAALOX15MEN1 | |
| Methacrylic Acid SCHEMBL9652589 | 0.71 | MAPT (0.43) | MAPTGAAMEN1KMT2AHSD17B10 | |
| SCHEMBL2312864 | 0.71 | NOX1 (0.57) | NOX1MAPTGAAALOX15MEN1 | |
| Phenothiazine SCHEMBL28750254 | 0.70 | NOX1 (0.71) | NOX1MAPTGAAALOX15MEN1 | |
| Phenothiazine SCHEMBL10460965 | 0.70 | NOX1 (0.49) | NOX1MAPTGAAALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155148-A | For stabilizing oxidizable rubbers, oils; co-polymerizable through unsaturated site | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0420790-A1 | Ester derivatives from p-hydroxydiphenylamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |