Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL29875738 | 0.77 | MAPT (0.61) | MAPTALDH1A1GAAHSP90AA1POLB | |
| Methacrylic Acid SCHEMBL9652583 | 0.75 | MAPT (0.42) | MAPTALDH1A1GAAHSP90AA1POLB | |
| SCHEMBL13335351 | 0.74 | ALDH1A1 (0.52) | MAPTALDH1A1GAAHSP90AA1MEN1 | |
| Diphenylamine SCHEMBL16552456 | 0.72 | MAPT (0.55) | MAPTALDH1A1GAAHSP90AA1POLB | |
| SCHEMBL75088 | 0.72 | RAB9A (0.53) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| Biphenyl SCHEMBL28090713 | 0.71 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDKMT2ATHRB | |
| Methacrylic Acid SCHEMBL28137373 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPK1LMNAKMT2AHTT | |
| Methacrylic Acid SCHEMBL8763652 | 0.71 | GRIK1 (0.42) | ALDH1A1THRBRAB9ASMN1; SMN2TRPV1 | |
| Methacrylic Acid SCHEMBL19194 | 0.71 | SMN1; SMN2 (0.52) | MAPTALDH1A1POLBMAPK1LMNA | |
| Bromobenzene SCHEMBL27405496 | 0.70 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155148-A | For stabilizing oxidizable rubbers, oils; co-polymerizable through unsaturated site | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0420790-A1 | Ester derivatives from p-hydroxydiphenylamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |