Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650567 | 0.95 | ALDH1A1 (0.48) | ALDH1A1TSHRCA1CA2CYP19A1 | |
| SCHEMBL243792 | 0.76 | TSHR (0.42) | ALDH1A1TSHRMAOBSMN1; SMN2 | |
| SCHEMBL28682858 | 0.72 | MAOB (0.54) | ALDH1A1TSHRCA1CA2LTA4H | |
| SCHEMBL9652517 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRCA1CA2HDAC8 | |
| SCHEMBL368442 | 0.71 | ALDH1A1 (0.78) | ALDH1A1TSHRCYP19A1MAOBNFE2L2 | |
| SCHEMBL16499669 | 0.71 | ALDH1A1 (0.78) | ALDH1A1TSHRCYP19A1MAOBNFE2L2 | |
| SCHEMBL8992497 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRCA1CA2POLB | |
| SCHEMBL9806380 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TSHRCA1CA2POLB | |
| SCHEMBL1562120 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TSHRCA1CA2POLB | |
| SCHEMBL1732811 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TSHRCA1CYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243006-B1 | BLOCK-GRAFT COPOLYMERS AND PROCESS FOR PRODUCING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4864003-A | Block-graft polymer and process for producing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4803243-A | Block-graft copolymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0243006-A2 | Block-graft copolymers and process for producing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |