Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169409 | 0.83 | TSHR (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL3683423 | 0.79 | TSHR (0.46) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9650567 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TSHRPOLBCA1CA2 | |
| SCHEMBL9806380 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRPOLBCA1CA2 | |
| SCHEMBL1562120 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRPOLBCA1CA2 | |
| SCHEMBL29253333 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRPOLBCA1CA2 | |
| Styrene SCHEMBL490169 | 0.71 | ALDH1A1 (0.93) | ALDH1A1TSHRPOLBLMNATDP1 | |
| SCHEMBL2498577 | 0.71 | LTA4H (0.53) | TSHRCA1CA2 | |
| SCHEMBL9650574 | 0.70 | ALDH1A1 (0.45) | ALDH1A1TSHRPOLBCA1CA2 | |
| Styrene SCHEMBL2831366 | 0.69 | ALDH1A1 (0.61) | ALDH1A1TSHRPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |