Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637977 | 0.81 | MAPT (0.42) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL9652020 | 0.74 | FFAR1 (0.40) | MEN1KMT2ANPC1MAPT | |
| SCHEMBL9638237 | 0.65 | CA1 (0.34) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL17285639 | 0.63 | MEN1 (0.51) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL11217664 | 0.61 | ESR1 (0.49) | MEN1KMT2ANPC1ESR1MAPT | |
| SCHEMBL9193227 | 0.60 | CA1 (0.41) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL3650882 | 0.60 | CA1 (0.41) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL8573268 | 0.60 | CA1 (0.41) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL3902576 | 0.60 | MEN1 (0.49) | MEN1KMT2ANPC1 | |
| SCHEMBL14319853 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0440809-A1 | METHYLENEDIPHOSPHONIC ACID COMPOUND AND ANTI-INFLAMMATORY CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 1991-08-14 | — | — | EP | disclosed |