Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245074 | 0.89 | ALDH1A1 (0.45) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9653663 | 0.81 | HDAC6 (0.44) | MAPK1 | |
| SCHEMBL9655310 | 0.80 | HTT (0.45) | KDM4EMAPK1NPSR1ALDH1A1GABRA1 | |
| SCHEMBL6148137 | 0.80 | LMNA (0.65) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL10864377 | 0.80 | DHODH (0.40) | MAPK1ALDH1A1DHODHMAPTSLC22A12 | |
| SCHEMBL9654636 | 0.80 | EGLN1 (0.38) | KDM4EDHODH | |
| SCHEMBL2313077 | 0.78 | LMNA (0.51) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11712521 | 0.77 | LMNA (0.54) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL8296199 | 0.76 | ERN1 (0.42) | KDM4ENPSR1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL13652292 | 0.75 | LMNA (0.47) | LMNAKDM4EMAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496332-A1 | Alpha-aminoquinolinoyl-[3]-penicillines, process for their preparation and their use as antibacterial agents | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |