Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377092 | 0.83 | MGAM (0.40) | ERN1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL11116001 | 0.82 | MAOA (0.44) | ERN1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL10807704 | 0.81 | SLC22A12 (0.37) | ALDH1A1KDM4EDHODHMEN1KMT2A | |
| SCHEMBL8302290 | 0.79 | MEN1 (0.45) | ALDH1A1HPGDKDM4ECYP2C9CYP1A2 | |
| SCHEMBL10864377 | 0.78 | DHODH (0.40) | ALDH1A1DHODHMAPTTHRB | |
| SCHEMBL9655310 | 0.78 | HTT (0.45) | ALDH1A1KDM4EHTTDHODHSMN1; SMN2 | |
| SCHEMBL8411036 | 0.78 | KDM4E (0.46) | ALDH1A1ALOX15HSD17B10KDM4EHTT | |
| SCHEMBL2310581 | 0.77 | ERN1 (0.50) | ERN1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL11245074 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL9652122 | 0.76 | LMNA (0.51) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900794-A1 | Light stabilizers based on sterically hindered amines | Clariant GmbH (DE) | 1999-03-10 | — | — | EP | disclosed |
| EP-0900824-A1 | 4-Hydroxyquinoline-3-carboxylic acid derivatives as light stabilizers | Clariant GmbH (DE) | 1999-03-10 | — | — | EP | disclosed |
| EP-0022078-B1 | PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | disclosed |
| EP-0022078-A1 | Pyrazolo-quinolines, processes for their production, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-01-07 | — | — | EP | disclosed |
| EP-0000203-A1 | 1-Ethyl-7-chloro-6-fluoro-4-quinolone-3-carboxylic acid, its preparation and application as plant bactericide | CIBA-GEIGY AG (CH) | 1979-01-10 | — | — | EP | disclosed |