SCHEMBL965272

SCHEMBL965272

NC(=O)[C@H](N)CCC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.68
GRM6 O15303 1/20 0.68
GRIN2D O15399 1/20 0.68
GRIN3B O60391 1/20 0.68
GSR P00390 1/20 0.68
CYP1A2 P05177 1/20 0.68
GRIK1 P39086 1/20 0.68
GRM5 P41594 1/20 0.68
GRIA1 P42261 1/20 0.68
GRIA2 P42262 1/20 0.68
GRIA3 P42263 1/20 0.68
SLC1A3 P43003 1/20 0.68
SLC1A2 P43004 1/20 0.68
SLC1A1 P43005 1/20 0.68
GRIA4 P48058 1/20 0.68
GRIN1 Q05586 1/20 0.68
GRIN2A Q12879 1/20 0.68
GRIK2 Q13002 1/20 0.68
GRIK3 Q13003 1/20 0.68
GRIN2B Q13224 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30022755 1.00 GRM8 (0.68) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL93831 1.00 GRM8 (0.68) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29438088 1.00 GRM8 (0.68) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL30571083 1.00 GRM8 (0.68) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL93830 1.00 GRM8 (0.68) GRM8GRM6GRIN2DGRIN3BGSR
Bromide SCHEMBL31300189 0.97 GRM8 (0.65) GRM8GRM6GRIN2DGRIN3BGSR
Hydrochloric Acid SCHEMBL18173930 0.97 GRM8 (0.65) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL10361106 0.97 GRM8 (0.65) GRM8GRM6GRIN2DGRIN3BGSR
Hydrochloric Acid SCHEMBL2251424 0.97 GRM8 (0.65) GRM8GRM6GRIN2DGRIN3BGSR
Water SCHEMBL2288176 0.97 GRM8 (0.65) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378328-B2 Biohybrid peptidoglycan oligomers NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-08-05 US claimed
US-20240041798-A1 OVARIAN CANCER VACCINES THE CLEVELAND CLINIC FOUNDATION 2024-02-08 US claimed
CN-117466978-A Muramyl dipeptide structure modification and reconstruction method and application thereof in lipid nanoparticle and nucleic acid drug delivery 中国药科大学 2024-01-30 CN claimed
US-11786489-B2 Ovarian cancer vaccines THE CLEVELAND CLINIC FOUNDATION (US) 2023-10-17 US claimed
CN-112805305-B Biohybrid peptidoglycan oligomers 南洋理工大学 2023-03-21 CN claimed
US-20220213232-A1 BIOHYBRID PEPTIDOGLYCAN OLIGOMERS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-07 US claimed
US-11090284-B2 Ovarian cancer vaccines THE CLEVELAND CLINIC FOUNDATION (US) 2021-08-17 US claimed
US-20110002983-A1 COMPOUND IMUTHES LIMITED (GB) 2011-01-06 US claimed
EP-4417216-B1 STABLE FORMULATIONS OF NEISSERIA MENINGITIDIS RLP2086 ANTIGENS WYETH LLC (US) 2026-01-28 EP disclosed
US-12492222-B2 Lipophilic enantiomers of desacetylglucosamine muramyl dipeptide with anti-inflammatory and growth promoting activity NUTRIVERT INC. (US) 2025-12-09 US disclosed
US-20250359575-A1 METHOD FOR IMPROVING FLAVOR OF FOOD AJINOMOTO CO., INC. (JP) 2025-11-27 US disclosed
EP-4642479-A1 MODIFIED BCG VACCINE University of the Witwatersrand, Johannesburg (ZA) 2025-11-05 EP disclosed
US-20250268839-A1 PROMOTING TRAINED IMMUNITY WITH THERAPEUTIC NANOBIOLOGIC COMPOSITIONS STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM (NL) 2025-08-28 US disclosed
US-12378328-B2 Biohybrid peptidoglycan oligomers NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-08-05 US disclosed
CN-1512890-A HCG formulation 开米卡公司 2004-07-14 CN disclosed
EP-1131354-A4 CONTRACEPTIVE ANTIBODY VACCINES EURO CELTIQUE SA (LU) 2003-01-02 EP disclosed
EP-1218499-A2 RESCUE OF MUMPS VIRUS FROM cDNA Wyeth (US) 2002-07-03 EP disclosed
EP-1131354-A1 CONTRACEPTIVE ANTIBODY VACCINES Euro-Celtique, S.A. (LU) 2001-09-12 EP disclosed
WO-2001009309-A2 RESCUE OF MUMPS VIRUS FROM cDNA AMERICAN HOME PRODUCTS CORPORATION (US) 2001-02-08 WO disclosed
WO-2000029443-A1 CONTRACEPTIVE ANTIBODY VACCINES EURO-CELTIQUE, S.A. (LU) 2000-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378328-B2 Biohybrid peptidoglycan oligomers NOD2, DDOST, CD14 GRM8 2869/4885GRM6 3101/4885GRIN2D 4129/4885
US-20220213232-A1 BIOHYBRID PEPTIDOGLYCAN OLIGOMERS NOD2, DDOST, CD14 GRM8 2869/4885GRM6 3101/4885GRIN2D 4129/4885
US-20110002983-A1 COMPOUND C5AR1, C5AR2, ARG1 GRM8 1896/4885GRM6 1282/4885GRIN2D 3925/4885
US-12492222-B2 Lipophilic enantiomers of desacetylglucosamine muramyl dipeptide with anti-inflammatory and growth promoting activity MIF, DNPEP, GLMN GRM8 1607/4885GRM6 890/4885GRIN2D 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.