Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 4/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653184 | 1.00 | COMT (0.42) | COMTFTOTDP1ATMKCNMA1 | |
| SCHEMBL9650649 | 0.86 | COMT (0.43) | COMTFTOKCNMA1MAPTKMT2A | |
| SCHEMBL9653250 | 0.86 | CES2 (0.47) | COMTFTOTDP1L3MBTL1MAPT | |
| SCHEMBL9650642 | 0.86 | COMT (0.43) | COMTFTOKCNMA1MAPTKMT2A | |
| SCHEMBL9653248 | 0.86 | CES2 (0.47) | COMTFTOTDP1L3MBTL1MAPT | |
| SCHEMBL9650742 | 0.85 | VCAM1 (0.45) | COMTFTOL3MBTL1HPGD | |
| SCHEMBL9652769 | 0.85 | COMT (0.42) | COMTFTOMAPTKMT2AMEN1 | |
| SCHEMBL9650751 | 0.85 | VCAM1 (0.45) | COMTFTOL3MBTL1HPGD | |
| SCHEMBL9652763 | 0.85 | COMT (0.42) | COMTFTOMAPTKMT2AMEN1 | |
| SCHEMBL9651847 | 0.85 | HPD (0.46) | COMTFTOTDP1KCNMA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |