Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317617 | 0.74 | HPRT1 (0.54) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28538940 | 0.73 | CYP1A2 (0.48) | CYP1A2CYP2A6BACE1CYP2C19TNKS2 | |
| SCHEMBL292398 | 0.72 | CYP1A2 (0.40) | CYP1A2CYP2A6BACE1CYP2C19TNKS2 | |
| SCHEMBL3112841 | 0.72 | HPRT1 (0.50) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18317355 | 0.72 | CYP1A2 (0.38) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL598701 | 0.70 | CYP1A2 (0.61) | CYP1A2CYP2A6BACE1CYP2C19TNKS2 | |
| SCHEMBL669061 | 0.68 | CYP1A2 (0.46) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL599191 | 0.64 | CYP1A2 (0.62) | CYP1A2CYP2A6BACE1ALDH1A1HPGD | |
| SCHEMBL598688 | 0.64 | CYP1A2 (0.68) | CYP1A2CYP2A6BACE1CYP2C19TNKS2 | |
| SCHEMBL31235727 | 0.64 | HPRT1 (0.64) | CYP1A2CYP2A6CYP2C19ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722956-B2 | Kit for decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2014-05-13 | — | — | US | claimed |
| WO-2013033830-A1 | METHOD FOR THE DETECTION OF CHEMICAL WARFARE AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-03-14 | — | — | WO | claimed |
| EP-1613402-B1 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | UNIV KINGSTON (CA) | 2013-01-16 | — | — | EP | claimed |
| US-20110253580-A1 | Method of Decomposing Organophosphorus Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-10-20 | — | — | US | claimed |
| US-7875739-B2 | Detoxification of hazardous materials; rapid lanthanum ion catalyzed alcoholysis | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-01-25 | — | — | US | claimed |
| US-20070299275-A1 | Method of decomposing organophosphorus compounds | BROWN R S | 2007-12-27 | — | — | US | claimed |
| EP-1613402-A2 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2006-01-11 | — | — | EP | claimed |
| US-20040230082-A1 | Method of decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-11-18 | — | — | US | claimed |
| WO-2004080543-A2 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-09-23 | — | — | WO | claimed |
| US-8722956-B2 | Kit for decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2014-05-13 | — | — | US | disclosed |
| WO-2013033830-A1 | METHOD FOR THE DETECTION OF CHEMICAL WARFARE AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-03-14 | — | — | WO | disclosed |
| EP-1613402-B1 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | UNIV KINGSTON (CA) | 2013-01-16 | — | — | EP | disclosed |
| US-20110253580-A1 | Method of Decomposing Organophosphorus Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-10-20 | — | — | US | disclosed |
| US-7875739-B2 | Detoxification of hazardous materials; rapid lanthanum ion catalyzed alcoholysis | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-01-25 | — | — | US | disclosed |
| US-20070299275-A1 | Method of decomposing organophosphorus compounds | BROWN R S | 2007-12-27 | — | — | US | disclosed |
| US-7214836-B2 | Method of decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-05-08 | — | — | US | disclosed |
| EP-1613402-A2 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2006-01-11 | — | — | EP | disclosed |
| US-20040230082-A1 | Method of decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-11-18 | — | — | US | disclosed |
| WO-2004080543-A2 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299275-A1 | Method of decomposing organophosphorus compounds | ACHE, L3MBTL3, L3MBTL4 | CYP1A2 1418/4885CYP2A6 1306/4885BACE1 1248/4885 |
| US-20040230082-A1 | Method of decomposing organophosphorus compounds | ACHE, L3MBTL3, L3MBTL4 | CYP1A2 1418/4885CYP2A6 1306/4885BACE1 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.