Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731545 | 0.71 | ADORA2A (0.35) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL25120296 | 0.58 | IKBKB (0.35) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL31685305 | 0.57 | ADORA2A (0.52) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL18758775 | 0.56 | LMNA (0.44) | LMNAALDH1A1CYP1A2BCAT2HPGD | |
| SCHEMBL5041494 | 0.56 | BCAT2 (0.33) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL23122685 | 0.56 | GDA (0.43) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL16131592 | 0.55 | RAB9A (0.49) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| Paraxanthine SCHEMBL31604159 | 0.55 | CYP3A4 (0.96) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| Bromide SCHEMBL23247973 | 0.55 | GDA (0.42) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL16975071 | 0.55 | LMNA (0.49) | LMNAALDH1A1MAPTTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164511-A | Thioimideazoles useful as intermediates for preparing thiazine | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5164511-A | Thioimideazoles useful as intermediates for preparing thiazine | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| WO-1992018509-A1 | BIOLOGICALLY ACTIVE THIAZINE | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5106969-A | Biologically active thiazine | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-04-21 | — | — | US | disclosed |