Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95681 | 0.75 | HDAC7 (0.46) | CA12CA9LMNA | |
| SCHEMBL10788448 | 0.69 | BACE1 (0.50) | ALDH1A1MAOBMAOAPARP10PARP11 | |
| SCHEMBL17264241 | 0.63 | ALOX5 (0.44) | ALDH1A1CYP3A4MAOBMAOABACE1 | |
| SCHEMBL784740 | 0.62 | — | — | |
| SCHEMBL11257546 | 0.61 | BACE1 (0.41) | ALDH1A1CYP3A4MAOBMAOABACE1 | |
| SCHEMBL10622407 | 0.60 | PARP10 (0.45) | ALDH1A1PARP10PARP11BACE1ALOX5 | |
| SCHEMBL1513749 | 0.59 | PDE4B (0.54) | EGFRPDE4BALDH1A1CYP3A4BACE1 | |
| SCHEMBL8160364 | 0.58 | MAOA (0.43) | MAOBMAOABACE1ALOX5 | |
| SCHEMBL15167033 | 0.58 | PDE4B (0.67) | EGFRPDE4BALDH1A1CYP3A4BACE1 | |
| SCHEMBL20820918 | 0.58 | TSHR (0.58) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |