Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439785 | 0.83 | HAVCR2 (0.68) | HAVCR2ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL11867822 | 0.81 | HAVCR2 (0.70) | HAVCR2ALDH1A1HTTMAPTHPGD | |
| SCHEMBL27348251 | 0.80 | HAVCR2 (0.41) | HAVCR2ALDH1A1HTTMAPTHPGD | |
| Hydrochloric Acid SCHEMBL11869520 | 0.79 | HAVCR2 (0.68) | HAVCR2ALDH1A1HTTMAPTHPGD | |
| SCHEMBL6200696 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTKDM4EMEN1 | |
| SCHEMBL27784060 | 0.77 | LMNA (0.46) | HAVCR2ALDH1A1HTTMAPTHPGD | |
| SCHEMBL9654332 | 0.77 | HTT (0.37) | HAVCR2ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL6201385 | 0.75 | EGLN1 (0.52) | ALDH1A1HTTHPGDKDM4ELMNA | |
| SCHEMBL9655373 | 0.74 | DHODH (0.43) | HAVCR2ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6201208 | 0.74 | ALB (0.40) | HAVCR2ALDH1A1HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496332-A1 | Alpha-aminoquinolinoyl-[3]-penicillines, process for their preparation and their use as antibacterial agents | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |