SCHEMBL463370

SCHEMBL463370

CCCCCCCCCCSCCN1CCCC1=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PIK3CD O00329 1/20 0.42
KMT2A Q03164 3/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.39
PKM P14618 1/20 0.39
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
NPC1 O15118 2/20 0.38
TSHR P16473 1/20 0.38
BRD4 O60885 1/20 0.37
BRD2 P25440 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056134 1.00 ALOX5 (0.43) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL28520481 0.94 GAA (0.42) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL9056711 0.94 ALOX5 (0.46) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL7801728 0.94 ALOX5 (0.46) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL9056157 0.94 RAB9A (0.43) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL7801906 0.89 RAB9A (0.42) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL7802935 0.88 GAA (0.42) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL9653498 0.88 GAA (0.42) ALOX5PIK3CDKMT2AGAARAB9A
SCHEMBL9654604 0.86 PIK3CD (0.47) PIK3CDKMT2ARAB9AMEN1PKM
SCHEMBL297738 0.84 ALOX5 (0.53) ALOX5PIK3CDKMT2AGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215888-A1 TOPICAL NAIL FORMULATION NUVO RESEARCH INC. (CA) 2009-08-27 US claimed
EP-1909772-A1 TRANSDERMAL DRUG DELIVERY FORMULATION Nuvo Research Inc. (CA) 2008-04-16 EP claimed
US-20070269379-A1 Penetration Enhancer Combinations for Transdermal Delivery REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2007-11-22 US claimed
WO-2007098591-A2 TOPICAL NAIL FORMULATION NUVO RESEARCH INC. (CA) 2007-09-07 WO claimed
US-20070184114-A1 Formulation for topical non-invasive application in vivo IDEA AG (DE) 2007-08-09 US claimed
WO-2007016766-A1 TRANSDERMAL DRUG DELIVERY FORMULATION NUVO RESEARCH INC. (CA) 2007-02-15 WO claimed
US-7137975-B2 Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent ACIONT, INC. (US) 2006-11-21 US claimed
WO-2005009510-A2 PENETRATION ENHANCER COMBINATIONS FOR TRANSDERMAL DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-03 WO claimed
EP-1140021-B1 IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO IDEA AG (DE) 2004-08-04 EP claimed
US-6620788-B1 Enteral sorbefacients HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2003-09-16 US claimed
US-5371238-A Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1994-12-06 US claimed
EP-0610502-A1 EMULSION CONTAINING PARATHYROID HORMONE FOR PERNASAL ADMINISTRATION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1994-08-17 EP claimed
US-5281580-A Respiratory system disorders TOYO JOZO COMPANY, LTD. (JP) 1994-01-25 US claimed
EP-0471618-B1 CALCITONIN-CONTAINING EMULSION FOR NASAL ADMINISTRATION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1993-09-29 EP claimed
EP-0555483-A1 PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE Hisamitsu Pharmaceutical Co., Inc. (JP) 1993-08-18 EP claimed
EP-0241050-B1 AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATION CONTAINING THE ABSORPTION PROMOTERS HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1992-10-14 EP claimed
EP-0471618-A1 Calcitonin-containing emulsion for nasal administration Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-02-19 EP claimed
US-4882359-A USED WITH DRUGS HISAMITSU PHARMACEUTICAL CO., LTD. (JP) 1989-11-21 US claimed
WO-1987006226-A2 AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATIONS CONTAINING THE ABSORPTION PROMOTERS HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1987-10-22 WO claimed
EP-0241050-A2 Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparation containing the absorption promoters HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1987-10-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070184114-A1 Formulation for topical non-invasive application in vivo GPX4, LPO, MMP8 ALOX5 68/4885PIK3CD 3109/4885KMT2A 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.