Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509995 | 0.85 | KMT2A (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL10878812 | 0.82 | DHODH (0.54) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL11686280 | 0.81 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL8625262 | 0.81 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL7644622 | 0.81 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL8991598 | 0.79 | CA1 (0.53) | CYP3A4CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL11751672 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PTPN12ALOX15KMT2ATDP1 | |
| SCHEMBL2876296 | 0.76 | ALOX15 (0.58) | ALDH1A1PTPN12ALOX15KMT2AHTT | |
| SCHEMBL2876298 | 0.76 | ALOX15 (0.58) | ALDH1A1PTPN12ALOX15KMT2AHTT | |
| SCHEMBL11882646 | 0.73 | MMP2 (0.50) | CYP3A4ALDH1A1KMT2AFAAHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151333-A | Containing imine derivative | NIPPON ZEON CO., LTD (JP) | 1992-09-29 | — | — | US | disclosed |