Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659562 | 0.90 | ALDH1A1 (0.47) | TTRNUDT1ALDH1A1PGRGAA | |
| SCHEMBL9657987 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9658026 | 0.86 | TTR (0.47) | TTRNUDT1ALDH1A1HSD17B10PDGFRA | |
| SCHEMBL9655015 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659017 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659170 | 0.82 | HSD17B10 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660343 | 0.82 | PKM (0.48) | TTRALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9654937 | 0.80 | TOP2A (0.49) | NUDT1ALDH1A1PGRGAAPTGS1 | |
| SCHEMBL19612272 | 0.80 | ALDH1A1 (0.48) | TTRALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL9660610 | 0.79 | ALDH1A1 (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |