Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257119 | 0.85 | ADRB2 (0.68) | KMT2AMEN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL4196759 | 0.83 | KMT2A (0.53) | KMT2AMEN1RAB9AALDH1A1PKM | |
| SCHEMBL7690294 | 0.81 | L3MBTL1 (0.58) | KMT2AMEN1RAB9AALDH1A1NPSR1 | |
| SCHEMBL28727682 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2299495 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2292061 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2292066 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2292479 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2295250 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL2292475 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518939-A1 | ANTIARRHYTHMIC AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013865-A1 | ANTIARRHYTHMIC AGENTS | ISIS INNOVATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |