Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719183 | 0.88 | ADRB2 (0.63) | L3MBTL1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL4209781 | 0.86 | L3MBTL1 (0.51) | L3MBTL1KMT2ARAB9AMEN1NPC1 | |
| Bromide SCHEMBL7678900 | 0.84 | KMT2A (0.57) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL9655113 | 0.81 | KMT2A (0.68) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL27520599 | 0.78 | L3MBTL1 (0.64) | L3MBTL1KMT2ARAB9AMEN1NPC1 | |
| Bromide SCHEMBL7679342 | 0.78 | ALDH1A1 (0.53) | L3MBTL1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL10453566 | 0.78 | L3MBTL1 (0.62) | L3MBTL1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL30196559 | 0.78 | L3MBTL1 (0.62) | L3MBTL1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL20553006 | 0.77 | ADRB2 (0.59) | ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL6859005 | 0.76 | L3MBTL1 (0.68) | L3MBTL1KMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376488-B1 | SPECIFIC ADRENORECEPTOR ANTAGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA, BLADDER OUTLET OBSTRUCTION, NEUROGENIC BLADDER, AND GYNECOLOGICAL SYNDROMES | ABBOTT LABORATORIES | 2002-04-23 | — | — | US | disclosed |