Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656203 | 1.00 | METAP2 (0.33) | METAP2NPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9655165 | 0.78 | SCN5A (0.34) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9655167 | 0.78 | SCN5A (0.34) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9655498 | 0.73 | HTT (0.38) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9655492 | 0.73 | HTT (0.38) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9654567 | 0.72 | TP53 (0.44) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9654577 | 0.72 | TP53 (0.44) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL10840042 | 0.70 | MAPT (0.40) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL1278627 | 0.70 | MAPT (0.40) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL1278625 | 0.70 | MAPT (0.40) | NPC1ALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099016-A | Mitomycin analogs containing 7-alkoxy groups and disulfides as antibiotics | BRISTOL-MYERS COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5097036-A | Mitomycin analogs; antibiotics antitumor agents | BRISTOL-MYERS COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4927943-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-05-22 | — | — | US | disclosed |