Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656966 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL9536018 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL11087821 | 0.74 | TSHR (0.49) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL9658189 | 0.74 | KMT2A (0.50) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL9539004 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL11307832 | 0.71 | HPGD (0.66) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL7208803 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL13478283 | 0.69 | MEN1 (0.55) | ALDH1A1MAPK1LMNAMAPTHSD17B10 | |
| SCHEMBL3015778 | 0.69 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL9535762 | 0.69 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |