Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492017 | 0.80 | TSHR (0.62) | ALDH1A1MAPK1TSHRCTSDCAPN1 | |
| SCHEMBL9535568 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTLMNA | |
| SCHEMBL9536018 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1TSHRMAPTLMNA | |
| SCHEMBL9655290 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPK1TSHRMAPTPKM | |
| SCHEMBL5384243 | 0.72 | L3MBTL1 (0.61) | ALDH1A1MAPK1TSHRL3MBTL1MAPT | |
| SCHEMBL8884629 | 0.69 | MAPK1 (0.56) | ALDH1A1MAPK1TSHRL3MBTL1MAPT | |
| SCHEMBL9656966 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPK1TSHRMAPTLMNA | |
| SCHEMBL3015778 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPK1TSHRL3MBTL1MAPT | |
| SCHEMBL11741174 | 0.68 | MAPK1 (0.53) | ALDH1A1MAPK1TSHRCTSDCAPN1 | |
| Nitric Acid SCHEMBL11144683 | 0.68 | TSHR (0.50) | ALDH1A1MAPK1TSHRCTSDCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |