SCHEMBL9655346

SCHEMBL9655346

C=C(C)COc1cc(N2C(=O)CC(=C(C)C)C2=O)c(Cl)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
PKM P14618 1/20 0.49
PPOX P50336 4/20 0.36
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 4/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
FKBP1A P62942 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.32
HTR2B P41595 2/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656383 0.91 PPOX (0.45) GAAPKMPPOX
SCHEMBL9655595 0.89 GAA (0.56) GAAPKMPPOXLMNAL3MBTL1
SCHEMBL9654864 0.86 GAA (0.52) GAAPKMPPOXLMNAL3MBTL1
SCHEMBL9656117 0.86 GAA (0.55) GAAPKMPPOXLMNAL3MBTL1
SCHEMBL9653058 0.85 PPOX (0.51) GAAPKMPPOXL3MBTL1MEN1
SCHEMBL9652343 0.84 PPOX (0.50) GAAPKMPPOXL3MBTL1MAPT
SCHEMBL9655608 0.84 GAA (0.45) GAAPKMPPOXL3MBTL1FKBP1A
SCHEMBL9654591 0.84 GAA (0.45) GAAPKMPPOXL3MBTL1POLB
SCHEMBL9655614 0.84 GAA (0.45) GAAPKMPPOXLMNAL3MBTL1
SCHEMBL9656477 0.84 PKM (0.71) GAAPKMPPOXLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed