SCHEMBL9655595

SCHEMBL9655595

CC(=O)COc1cc(N2C(=O)CC(=C(C)C)C2=O)c(Cl)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
PKM P14618 1/20 0.56
LMNA P02545 2/20 0.39
PPOX P50336 4/20 0.37
FKBP1A P62942 1/20 0.36
L3MBTL1 Q9Y468 6/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656349 0.91 PPOX (0.48) GAAPKMLMNAPPOXALDH1A1
SCHEMBL9656117 0.90 GAA (0.55) GAAPKMLMNAPPOXFKBP1A
SCHEMBL9655346 0.89 GAA (0.49) GAAPKMLMNAPPOXFKBP1A
SCHEMBL9654864 0.88 GAA (0.52) GAAPKMLMNAPPOXL3MBTL1
SCHEMBL9656477 0.88 PKM (0.71) GAAPKMLMNAPPOXL3MBTL1
SCHEMBL9654591 0.85 GAA (0.45) GAAPKMPPOXL3MBTL1ALDH1A1
SCHEMBL9652343 0.85 PPOX (0.50) GAAPKMPPOXL3MBTL1MAPT
SCHEMBL9655614 0.85 GAA (0.45) GAAPKMLMNAPPOXL3MBTL1
SCHEMBL9655608 0.85 GAA (0.45) GAAPKMPPOXFKBP1AL3MBTL1
SCHEMBL9655564 0.85 GAA (0.50) GAAPKMLMNAPPOXL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed