Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695101 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL8569247 | 0.84 | KMT2A (0.46) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL10693508 | 0.80 | KMT2A (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL11775052 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL11773794 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL11778394 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL8568846 | 0.78 | KMT2A (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12821356 | 0.78 | ALDH1A1 (0.71) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL9403533 | 0.78 | ALDH1A1 (0.71) | ALDH1A1LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL28138500 | 0.77 | ALDH1A1 (0.60) | ALDH1A1LMNATP53SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| US-5090991-A | HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES | BAYER AKATIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4968342-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |