Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655428 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL10693508 | 0.77 | KMT2A (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1ATM | |
| SCHEMBL8568846 | 0.76 | KMT2A (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL7621077 | 0.73 | TDP1 (0.43) | ALDH1A1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL11794701 | 0.72 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL10691887 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL9676729 | 0.71 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8569247 | 0.70 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL4437234 | 0.69 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KMT2ACYP3A4 | |
| SCHEMBL10695198 | 0.69 | L3MBTL1 (0.42) | ALDH1A1SMN1; SMN2TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |