SCHEMBL8569247

SCHEMBL8569247

CC(=O)OCC(=O)N(c1ccc(F)cc1)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 3/20 0.46
ATM Q13315 1/20 0.46
LMNA P02545 2/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MLYCD O95822 1/20 0.37
MC4R P32245 2/20 0.36
MC1R Q01726 2/20 0.36
CCKAR P32238 1/20 0.35
CCKBR P32239 1/20 0.35
S100A4 P26447 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655428 0.84 ALDH1A1 (0.61) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL5210618 0.81 LMNA (0.42) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL27528961 0.81 ALDH1A1 (0.42) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL8864904 0.79 ALDH1A1 (0.49) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL5718403 0.79 ALDH1A1 (0.49) KMT2AALDH1A1MEN1ATMLMNA
Acetic Acid SCHEMBL6262503 0.78 ALDH1A1 (0.49) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL5103764 0.78 ALDH1A1 (0.47) KMT2AALDH1A1MEN1ATMLMNA
SCHEMBL6938672 0.78 ALDH1A1 (0.70) KMT2AALDH1A1LMNATP53SMN1; SMN2
SCHEMBL13915059 0.77 S100A4 (0.45) KMT2AALDH1A1MEN1LMNATP53
SCHEMBL8654809 0.77 MAPT (0.38) KMT2AALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115901994-B Analysis method for content of flufenacet intermediate 山东京博农化科技股份有限公司 2025-04-25 CN claimed
CN-115901994-A Method for analyzing content of flufenacet intermediate 山东京博农化科技股份有限公司 2023-04-04 CN claimed
US-5808153-A Conversion of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide acetate to N-4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide BAYER CORPORATION 1998-09-15 US claimed
CN-115901994-B Analysis method for content of flufenacet intermediate 山东京博农化科技股份有限公司 2025-04-25 CN disclosed
CN-115901994-B Analysis method for content of flufenacet intermediate 山东京博农化科技股份有限公司 2025-04-25 CN disclosed
CN-115901994-A Method for analyzing content of flufenacet intermediate 山东京博农化科技股份有限公司 2023-04-04 CN disclosed
CN-115901994-A Method for analyzing content of flufenacet intermediate 山东京博农化科技股份有限公司 2023-04-04 CN disclosed
CN-1142924-C Process for producing thiadiazol acetamides deriv. 2004-03-24 CN disclosed
CN-1134424-C Process for making thiadiazol-acetamides deriv. using aprotic, aromatic solvent Ĭ��ר���ɷ����޹�˾ 2004-01-14 CN disclosed
CN-1224007-A Process for producing thiadiazol acetamides deriv. BAYER AG (US) 1999-07-28 CN disclosed
CN-1224008-A Process for making thiadiazol-acetamides deriv. using aprotic, aromatic solvent BAYER AG (US) 1999-07-28 CN disclosed
US-5808152-A Synthesis of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide using sodium formate BAYER CORPORATION (US) 1998-09-15 US disclosed
US-5808153-A Conversion of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide acetate to N-4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide BAYER CORPORATION 1998-09-15 US disclosed
US-5808153-A Conversion of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide acetate to N-4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide BAYER CORPORATION 1998-09-15 US disclosed
US-5616799-A REACTING A CORRESPONDING NITRO COMPOUND WITH A KETONE AND HYDROGEN IN PRESENCE OF A NOBLE METAL CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed