Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839495 | 0.96 | TSHR (0.47) | LSSPPARGPTGS2APEX1POLB | |
| SCHEMBL9655690 | 0.91 | PPARG (0.46) | PPARGPTGS2HTTPTGS1MEN1 | |
| SCHEMBL9650794 | 0.91 | MAPT (0.48) | LSSPTGS2APEX1POLBHTT | |
| SCHEMBL9650790 | 0.91 | MAPT (0.48) | LSSPTGS2APEX1POLBHTT | |
| SCHEMBL9654849 | 0.85 | ALDH1A1 (0.42) | LSSPPARGPTGS2PTGS1TSHR | |
| SCHEMBL9654844 | 0.85 | ALDH1A1 (0.42) | LSSPPARGPTGS2PTGS1TSHR | |
| SCHEMBL8897411 | 0.84 | HTT (0.57) | LSSPTGS2APEX1POLBHTT | |
| SCHEMBL8897407 | 0.84 | HTT (0.57) | LSSPTGS2APEX1POLBHTT | |
| SCHEMBL10333121 | 0.84 | HTT (0.57) | LSSPTGS2APEX1POLBHTT | |
| SCHEMBL12895484 | 0.84 | ATM (0.46) | PPARGPOLBHTTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313476-B1 | AN OPTICAL ARTICLE CONTAINING A POLYMERIC MATRIX EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4796971-A | CHARGE TRANSFER COMPOUND ON CROSSLINKED MATRIX | EASTMAN KODAK COMPANY (US) | 1989-01-10 | — | — | US | disclosed |