Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655692 | 0.96 | LSS (0.41) | TSHRMAPTMEN1KMT2APTGS2 | |
| SCHEMBL9655690 | 0.88 | PPARG (0.46) | MAPTMEN1KMT2APTGS2LMNA | |
| SCHEMBL9650794 | 0.87 | MAPT (0.48) | TSHRMAPTMEN1KMT2APTGS2 | |
| SCHEMBL9650790 | 0.87 | MAPT (0.48) | TSHRMAPTMEN1KMT2APTGS2 | |
| SCHEMBL9798398 | 0.84 | TSHR (0.39) | TSHRNPSR1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9358492 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2APTGS2LMNA | |
| SCHEMBL592174 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2APTGS2LMNA | |
| SCHEMBL9358488 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2APTGS2LMNA | |
| SCHEMBL592173 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2APTGS2LMNA | |
| SCHEMBL9362316 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2APTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003002-A1 | PHOTO-CROSSLINKED POLYMERS FOR NON-LINEAR OPTICS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |