SCHEMBL7986272

SCHEMBL7986272

COC(=O)CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
ALOX5 P09917 7/20 0.52
NR1I2 O75469 2/20 0.52
MAPT P10636 2/20 0.51
LMNA P02545 2/20 0.51
MEN1 O00255 1/20 0.51
GSTP1 P09211 1/20 0.51
TTPA P49638 1/20 0.51
KMT2A Q03164 1/20 0.51
USP2 O75604 1/20 0.51
THRB P10828 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
CYP4F2 P78329 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816262 0.88 PTGS1 (0.54) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5773112 0.87 ALOX5 (0.57) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL6028036 0.85 CYP3A4 (0.63) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5674832 0.85 CYP3A4 (0.63) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5675007 0.85 CYP3A4 (0.63) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL9655733 0.84 CYP3A4 (0.58) PTGS1PTGS2CYP1A2CYP3A4TSHR
Ethane SCHEMBL4283975 0.84 CYP3A4 (0.62) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL9075119 0.84 MEN1 (0.59) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL9094963 0.82 CYP3A4 (0.56) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL9096916 0.82 CYP3A4 (0.56) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976084-B2 Liquid crystal composition, antioxidant and liquid crystal display device JNC CORPORATION (JP) 2018-05-22 US disclosed
US-20140183409-A1 LIQUID CRYSTAL COMPOSITION, ANTIOXIDANT AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-07-03 US disclosed
US-6235731-B1 REDUCING BLOOD LIPIDS, SUGARS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
EP-0915888-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS Takeda Chemical Industries, Ltd. (JP) 1999-05-19 EP disclosed
WO-1997040051-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-30 WO disclosed
US-4788214-A ANTIALLERGENS HOFFMAN-LA ROCHE INC. (US) 1988-11-29 US disclosed
US-4785017-A ANTIALLERGENS HOFFMANN-LA ROCHE INC. (US) 1988-11-15 US disclosed