Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655193 | 0.67 | LPAR1 (0.39) | LPAR1LPAR3PGK1PGK2 | |
| SCHEMBL1533912 | 0.63 | — | — | |
| SCHEMBL513412 | 0.61 | FDPS (0.31) | — | |
| SCHEMBL3392626 | 0.60 | — | — | |
| SCHEMBL1585488 | 0.60 | — | — | |
| SCHEMBL160868 | 0.60 | LPAR1 (0.68) | LPAR1LPAR3 | |
| SCHEMBL21228198 | 0.59 | — | — | |
| SCHEMBL18486612 | 0.58 | PGK1 (0.39) | LPAR1LPAR3PGK1PGK2 | |
| SCHEMBL4105275 | 0.58 | — | — | |
| SCHEMBL6246903 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479640-A2 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0477454-A1 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-01 | — | — | EP | disclosed |