Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238007 | 0.70 | FDPS (0.37) | FDPS | |
| SCHEMBL98484 | 0.70 | LMNA (0.39) | FDPS | |
| SCHEMBL3953784 | 0.62 | TSHR (0.30) | — | |
| SCHEMBL6307341 | 0.62 | FDPS (0.45) | FDPS | |
| SCHEMBL9655935 | 0.61 | LPAR1 (0.37) | — | |
| SCHEMBL8463440 | 0.61 | FDPS (0.37) | FDPS | |
| SCHEMBL7759899 | 0.61 | FDPS (0.37) | FDPS | |
| SCHEMBL6296955 | 0.58 | FDPS (0.43) | FDPS | |
| SCHEMBL246809 | 0.58 | FDPS (0.43) | FDPS | |
| SCHEMBL8718782 | 0.58 | GGPS1 (0.50) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | FDPS 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.