Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725073 | 0.81 | KDM4E (0.37) | AKT1POLBGAAHSD17B10ALDH1A1 | |
| SCHEMBL157513 | 0.80 | RAB9A (0.38) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL9652808 | 0.78 | POLB (0.36) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL156386 | 0.75 | ALDH1A1 (0.39) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL9652766 | 0.75 | POLB (0.36) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL136598 | 0.74 | MAPT (0.41) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL305024 | 0.74 | ALDH1A1 (0.37) | POLBGAAHSD17B10MAPTALDH1A1 | |
| SCHEMBL993045 | 0.73 | CES1 (0.45) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL363122 | 0.73 | MAPT (0.40) | POLBGAAHSD17B10HTTMAPT | |
| SCHEMBL156512 | 0.73 | MAPT (0.40) | POLBGAAHSD17B10HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155161-A | Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis | NIPPON ZEON CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0438248-A2 | Preparation process of toner | NIPPON ZEON CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |