Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632585 | 0.91 | DRD3 (0.74) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9634547 | 0.85 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9633140 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL12665447 | 0.80 | DRD3 (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL13923341 | 0.80 | DRD3 (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9633927 | 0.80 | DRD3 (0.68) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11067262 | 0.79 | KDM4E (0.80) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL10027766 | 0.79 | DRD3 (0.84) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL32659736 | 0.78 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL13923331 | 0.77 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162523-A | CEPHALOSPORIN ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |