Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887617 | 0.83 | SCN5A (0.40) | SMN1; SMN2KYAT1ALDH1A1TDP1GAA | |
| SCHEMBL7343923 | 0.83 | SCN5A (0.40) | SMN1; SMN2KYAT1ALDH1A1TDP1GAA | |
| SCHEMBL9655458 | 0.76 | EPHX1 (0.41) | ALDH1A1TDP1GAAMEN1KMT2A | |
| SCHEMBL9655455 | 0.76 | EPHX1 (0.41) | ALDH1A1TDP1GAAMEN1KMT2A | |
| SCHEMBL1278627 | 0.73 | MAPT (0.40) | SMN1; SMN2LMNAKYAT1ALDH1A1TDP1 | |
| SCHEMBL1278625 | 0.73 | MAPT (0.40) | SMN1; SMN2LMNAKYAT1ALDH1A1TDP1 | |
| SCHEMBL9655167 | 0.70 | SCN5A (0.34) | SMN1; SMN2LMNAKYAT1ALDH1A1TDP1 | |
| SCHEMBL7911594 | 0.70 | TDP1 (0.50) | SMN1; SMN2LMNAALDH1A1TDP1GAA | |
| SCHEMBL7793224 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1TDP1GAA | |
| SCHEMBL7793228 | 0.68 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099016-A | Mitomycin analogs containing 7-alkoxy groups and disulfides as antibiotics | BRISTOL-MYERS COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5097036-A | Mitomycin analogs; antibiotics antitumor agents | BRISTOL-MYERS COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4927943-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4814445-A | ETHERIFICATION, ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-03-21 | — | — | US | disclosed |