Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110086 | 0.97 | LMNA (0.42) | LMNAFOLH1ALDH1A1TDP1GSTK1 | |
| SCHEMBL28101183 | 0.95 | LMNA (0.39) | LMNAFOLH1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8884312 | 0.93 | LMNA (0.50) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL4610193 | 0.93 | LMNA (0.50) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL8883444 | 0.93 | LMNA (0.50) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL25826319 | 0.93 | LMNA (0.39) | LMNAFOLH1ALDH1A1TDP1 | |
| SCHEMBL4610338 | 0.90 | ALDH1A1 (0.41) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8883918 | 0.88 | ALDH1A1 (0.39) | LMNAFOLH1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL4608160 | 0.88 | LMNA (0.50) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL4610449 | 0.88 | LMNA (0.50) | LMNAALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240212-B1 | PREPARATION OF HIGHLY PURE ALPHA-METHYLSTYRENE POLYMER | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4748222-A | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0240212-A2 | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0058217-B1 | A PROCESS FOR PRODUCING A RANDOM COPOLYMER AND RANDOM COPOLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| EP-0058217-A1 | A process for producing a random copolymer and random copolymer | PHILLIPS PETROLEUM COMPANY (US) | 1982-08-25 | — | — | EP | disclosed |
| US-4277591-A | ORGANOLITHIUM INITIATOR AND AN ORGANIC COMPOUND OF SODIUM, POTASSIUM, RUBIDIUM, OR CESIUM | PHILLIPS PETROLEUM COMPANY (US) | 1981-07-07 | — | — | US | disclosed |