SCHEMBL25826319

SCHEMBL25826319

CCCC(CCS)CCCCCS

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
FOLH1 Q04609 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1110086 0.95 LMNA (0.42) LMNAFOLH1ALDH1A1TDP1
SCHEMBL9656242 0.93 LMNA (0.41) LMNAFOLH1ALDH1A1TDP1
SCHEMBL28101183 0.93 LMNA (0.39) LMNAFOLH1ALDH1A1TDP1
SCHEMBL4609781 0.91 LMNA (0.50) LMNA
SCHEMBL12226204 0.91 LMNA (0.50) LMNA
SCHEMBL8883444 0.91 LMNA (0.50) LMNAALDH1A1TDP1
SCHEMBL4610193 0.91 LMNA (0.50) LMNAALDH1A1TDP1
SCHEMBL8884312 0.91 LMNA (0.50) LMNAALDH1A1TDP1
SCHEMBL4610338 0.88 ALDH1A1 (0.41) LMNAALDH1A1TDP1
SCHEMBL4610132 0.88 LMNA (0.46) LMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023124857-A1 ANTIBODY AND USE THEREOF 合肥天港免疫药物有限公司 2023-07-06 WO disclosed