Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641857 | 0.82 | ABCB11 (0.62) | ABCB11KDM4EALDH1A1HSD17B10AKR1B1 | |
| SCHEMBL9657729 | 0.82 | MEN1 (0.37) | KDM4EALDH1A1CYP1A2HSD17B10TAS1R3 | |
| SCHEMBL9656402 | 0.81 | ABCB11 (0.41) | ABCB11KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL20398629 | 0.81 | HSD17B10 (0.48) | ABCB11KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9643543 | 0.81 | ABCB11 (0.41) | ABCB11ALDH1A1TAS1R3TAS1R1AKR1B1 | |
| SCHEMBL31080948 | 0.81 | HSD17B10 (0.48) | ABCB11KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9656750 | 0.78 | KDM4E (0.61) | ABCB11KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9643555 | 0.78 | ALDH1A1 (0.44) | ABCB11KDM4EALDH1A1HSD17B10AKR1B1 | |
| SCHEMBL9656140 | 0.78 | ABCB11 (0.49) | ABCB11KDM4ECYP1A2CYP2C9IDO1 | |
| SCHEMBL9658066 | 0.78 | ABCB11 (0.74) | ABCB11KDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |