Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656267 | 0.81 | ABCB11 (0.44) | ABCB11ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9657057 | 0.81 | PLK1 (0.39) | HSPD1HSPE1ALDH1A1PGRGAA | |
| SCHEMBL9654740 | 0.80 | ALDH1A1 (0.53) | ABCB11ALDH1A1PGRGAAPTGS1 | |
| SCHEMBL9641857 | 0.79 | ABCB11 (0.62) | ABCB11ALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL9656319 | 0.79 | ABCB11 (0.47) | ABCB11HSPD1HSPE1ALDH1A1PGR | |
| SCHEMBL9656448 | 0.79 | ABCB11 (0.70) | ABCB11ALDH1A1PGRGAAPTGS1 | |
| SCHEMBL11510164 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDACHERAF1KMT2A | |
| SCHEMBL10644830 | 0.76 | ABCB11 (0.43) | ABCB11ALDH1A1PGRGAAPTGS1 | |
| SCHEMBL9643543 | 0.75 | ABCB11 (0.41) | ABCB11ALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL9643555 | 0.75 | ALDH1A1 (0.44) | ABCB11ALDH1A1GAAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |